They were considered the most effective weight loss drugs available. But almost a decade after Fen-Phen was pulled off the shelves, researchers are still looking for a formula to slide the scales toward skinny.
Now a new clinical trial shows promise in melting away the pounds.
Like Fen-Phen, the trial combines two drugs already approved by the FDA where the side benefit has been weight loss. The idea is putting the two together will equal greater benefits for the patient.
One of those trying the medication says, "I don't feel as hungry. I feel like I'm more in control of when I'm eating instead of trying to eat everything in sight. I get full and I stop."
In this study, Wellbutrin, an anti-depressant, deals with seratonin, while an anti-seizure drug goes for the dopamine - another messenger that tells the brain the body's full.
Maria Lightford is one of 45 patients who will be followed for the next year. She says the early results are a boost that's helping her get on track to a healthy lifestyle.
And she welcomes whatever help she can get. "If it'll help you lose weight, why not?"
Doctors say the potential side effects of these drugs could include numbness, tingling and a feeling of fogginess.
Another phase of the trial will get underway in a matter of months.
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# posted by Network @ 11:29 PM
